ThreatLocker vs Uptycs: MDR Comparison 2026
Detailed comparison of ThreatLocker and Uptycs managed detection and response services. Compare response capabilities, SLA, coverage, integrations, and compliance.
Winner by Category
Response Level
Tie
Same level
SLA Speed
Tie
Same speed
Coverage Breadth
Uptycs
4 vs 3 surfaces
Integrations
Uptycs
More integration options
Criteria
Unmatched price-to-value ratio for Zero Trust MDR. The $2-5/user pricing with 60-second response time makes it the most affordable MDR option, ideal for MSPs and SMBs already using or willing to adopt ThreatLocker.
Uniquely positioned for cloud-native and hybrid environments with osquery-powered telemetry, eBPF monitoring, and unified CNAPP + MDR. Ideal for enterprises running Kubernetes at scale who need deep container and cloud workload security with DFIR capabilities.
Response Type
Active Remediation
Active Remediation
Approval Policy
Configurable
Configurable
Auto-Isolate
✓
✓
Kill Process
✓
✓
IR Included
Separate
✓ Included
Response SLA
60-second average response time
Contact for specific SLA commitments
24/7 Coverage
✓ Yes
✓ Yes
Channels
EmailPortalPhone
EmailPortalPhone
Data Access
Dashboards
Full Query
Model
Per-user per-month tiered pricing
Per-asset pricing with tiered packages (Discover, Audit, Secure); MDR services are custom-quoted add-ons
Price Range
$2-$5 per user per month for MDR add-on
Discover Workload: $3/month; Discover Cloud: $5/month; Audit Workload: $6/month; Audit Cloud: $10/month; Secure + MDR: custom. $12,000 minimum annual contract.
Minimum Seats
None
None
Threat Hunting
Extra cost
✓ Included
Overall
Very Positive
Positive
Summary
9.2/10 on PeerSpot with 100% willingness to recommend. MSPs praise the value proposition and support quality. Zero Trust approach is highly regarded. Interface speed and complexity are noted concerns.
Rated 8.0/10 on PeerSpot. Praised for real-time monitoring, seamless cloud deployment, and detailed reporting with osquery flexibility. Concerns about company stability due to quarterly layoffs reported by employees, and limited brand recognition outside cloud-native circles.
ThreatLocker vs Uptycs: Which Should You Choose?
Choose ThreatLocker if:
- You need active remediation
- 60-second average response time response time meets your needs
- You prefer platform native solutions
- Your org size: Mid-market / SMB / Enterprise
Choose Uptycs if:
- You need active remediation
- Contact for specific SLA commitments response time meets your needs
- You prefer platform native solutions
- Your org size: Enterprise
FAQ
What's the main difference between ThreatLocker and Uptycs?
Key differences: response model (Active Remediation vs Active Remediation), SLA (60-second average response time vs Contact for specific SLA commitments), and approach (Platform Native vs Platform Native).